Buy Glucophage (Metformin) Online without Prescription.
No prescription Needed. Free worldwide Shipping Fee.
Brand name: Glucophage
Generic Name : Metformin
Manufacturer : Merck
: Diabetes Drug
FDA Pregnant Category :
Category B : Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women, or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was notconfirmed in controlled studies in women in the first trimester (and there is no evidence of a risk in later trimesters).
What is it used for?
Type 2 (non-insulin dependent) diabetes, when diet has failed
How does it work?
People with type 2 diabetes (non-insulin dependent
diabetes) have a deficiency of a hormone called insulin. Insulin
is produced by the pancreas and is the main hormone responsible
for controlling sugar levels in the blood. It normally makes the
cells of the body remove excess sugar from the blood. In type
2 diabetes the cells of the body are also resistant to the action
of insulin that is produced, which means that blood sugar levels
can become too high.
Metformin hydrochloride is a type of antidiabetic
medicine known as a biguanide. It works in a number of ways to
decrease the amount of sugar in the blood of people with type
Firstly, it reduces the amount of sugar produced
by cells in the liver. Secondly, it increases the sensitivity
of muscle cells to insulin. This enables the cells to remove sugar
from the blood more effectively. Finally, it also delays absorption
of sugar from the intestines into the bloodstream after eating.
Overall, metformin reduces blood sugar levels both between and
directly after meals.
Metformin is used as a first line treatment of
type 2 diabetes, particularly in overweight people, when diet
and exercise have failed to control blood sugar levels. It can
also be used in combination with other antidiabetic medicines
to provide better control of blood sugar.
How should Glucophage (Metformin) be used ?
Glucophage comes in tablets to take by mouth.
It usually is taken two or three times a day with meals. Follow
the directions on your prescription label carefully, and ask your
doctor or pharmacist to explain any part you do not understand.
Take Glucophage exactly as directed. Do not take more or less
of it or take it more often than prescribed by your doctor. Metformin
hydrochloride extended-release tablets should be swallowed whole.
Do not break, chew, or crush.
Continue to take Metformin hydrochloride even
if you feel well. Do not stop taking Metformin hydrochloride without
talking to your doctor.
- People taking this medicine should have regular blood tests to monitor their kidney function.
- This medicine should be discontinued prior to X-ray examinations with iodinated materials, as a temporary decrease in kidney function may occur. It should not be reinstated until kidney function has been tested and found to be normal.
- Alcohol should be avoided while you are taking this medicine, as it can increase the risk of low blood sugar (hypoglycaemia) and lactic acidosis.
- Consult your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic. In these situations blood sugar is normally controlled by insulin, so your doctor may ask you to stop taking this medicine 48 hours before surgery.
- Blood sugar levels should be monitored while taking this medicine, particularly if it is taken with other oral antidiabetic medicines or insulin.
Not to be used in
- Alcoholic intoxication
- Cessation of breathing (respiratory failure)
- Coma due to ketoacidosis in severe and inadequately treated
diabetes (diabetic coma)
- Decreased kidney function
- Decreased liver function
- Heart failure
- Kidney failure
- People who have recently had a heart attack
- Reduced blood flow to vital internal organs (shock)
- Severe infections or trauma
This medicine should not be used if you are allergic
to one or any of its ingredients. Please inform your doctor or
pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic
reaction, stop using this medicine and inform your doctor or pharmacist
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy
or breastfeeding. However, other medicines may be safely used
in pregnancy or breastfeeding providing the benefits to the mother
outweigh the risks to the unborn baby.Always inform your doctor
if you are pregnant or planning a pregnancy, before using any
This medicine should not be used during pregnancy.
Control of diabetes mellitus in pregnancy is usually achieved
using insulin because it provides a more stable control of blood
sugar. Please consult with your doctor.
This medicine passes into breast milk. Breastfeeding mothers should
therefore either stop breastfeeding while taking this medicine,
or not take this medicine. Seek medical advice from your doctor.
Take this medication with or after food.
Medicines and their possible side effects can
affect individual people in different ways. The following are
some of the side effects that are known to be associated with
this medicine. Because a side effect is stated here, it does not
mean that all people using this medicine will experience that
or any side effect.
- Flushing of the skin due to widening of the small blood vessels
- Loss of appetite
- Elevated levels of lactic acid in the blood (lactic acidosis)
- Disturbances of the gut such as nausea, vomiting, diarrhoea
or abdominal pain
The side effects listed above may not include
all of the side effects reported by the drug's manufacturer.
For more information about any other possible
risks associated with this medicine, please read the information
provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other medicines ?
The following medicines can raise blood sugar
levels and may therefore oppose the effect of metformin:-
- corticosteroids, such as prednisolone
- diuretics, such as bendrofluazide
- beta-2-agonists, such as salbutamol.
Cimetidine may cause an increase in the blood
level of metformin. Your doctor may reduce your metformin dose
if you take both medicines.
When metformin is taken with other antidiabetic
medicines, such as sulphonylureas (eg gliclazide, glibenclamide)
or insulin, there will be an enhanced blood sugar lowering effect.
Blood sugar should be monitored.
Low blood sugar levels (hypoglycaemia) may occur,
sometimes unpredictably, if metformin is taken with ACE inhibitors
such as captopril.
Alcohol should be avoided while you are taking
this medicine, as it can increase the risk of hypoglycaemia and
This medicine should be discontinued prior to
X-ray examinations with iodinated materials, as a temporary decrease
in kidney function may occur. It should not be reinstated until
kidney function has been tested and found to be normal.
The usual starting dose is one 500-milligram
tablet twice a day, taken with morning and evening meals. Your
doctor may increase your daily dose by 500 milligrams at weekly
intervals, based on your response up to a total of 2,000 milligrams.
An alternative starting dose is one 850-milligram
tablet a day, taken with the morning meal. Your doctor may increase
this by 850 milligrams at 14-day intervals, to a maximum of 2,550
milligrams a day.
The usual maintenance dose ranges from 1,500
to 2,550 milligrams daily. If you take more than 2,000 milligrams
a day, your doctor may recommend that the medication be divided
into three doses, taken with each meal.
The usual starting dose is one 500-milligram
tablet once daily with the evening meal. Your doctor may increase
your dose by 500 milligrams at weekly intervals, up to a maximum
dosage of 2,000 milligrams a day. If a single 2,000-milligram
dose fails to control your blood sugar, you may be asked to take
1,000-milligram doses twice a day. If you need more than 2,000
milligrams a day, the doctor will switch you to regular Glucophage.
For children 10 to 16 years old, the usual starting
dose is one 500-milligram tablet twice a day with meals. The dosage
may be increased by 500 milligrams at weekly intervals up to a
maximum of 2,000 milligrams daily. Glucophage has not been tested
in children younger than 10.
This form of the drug has not been tested in children younger
Older people and those who are malnourished or
in a weakened state are generally given lower doses of Glucophage
because their kidneys may be weaker, making side effects more
An overdose of Glucophage can cause lactic acidosis.
If you suspect a Glucophage overdose, seek emergency treatment
When you miss a dose
Take it as soon as you remember. If it is almost
time for your next dose, skip the one you missed and go back to
your regular schedule. Never take 2 doses at the same time.
Store it at room temperature.
Our Most Popular Drugs
Antihistamine,Antiallergy,Minor Ranquillizer ,
Antiviral, Antifungals, Antiinfectives