Ventolin (Albuterol, Salbutamol)
Brand name : Ventolin
Generic Name : Albuterol ,Salbutamol
: Minor Ranquillizer& Antiasthmatic Preparation & Antihistamine
FDA Pregnant Category
Category C : Either studies in animals have revealed
adverse effects on the fetus (teratogenic or embryocidal or other)
and there are no controlled studies in women, or studies in women
and animals are not available. Drugs should be given only if the
potential benefit justifies the potential risk to the fetus.
What is it used for ?
- Chronic obstructive pulmonary disease (COPD)
How does it work ?
This medicine contains the active ingredient
salbutamol, which is a type of medicine known as a short-acting
beta 2 agonist. It works by acting on receptors in the lungs called
beta 2 receptors. Stimulation of these receptors causes the muscles
in the airways to relax, allowing the airways to open.
In conditions where there is narrowing of the
airways, such as asthma, emphysema and bronchitis, it is difficult
for air to get in and out of the lungs. By opening the airways,
salbutamol makes it easier to breathe.
Salbutamol is most commonly taken using an inhaler
device. Inhaling the medicine allows it to act directly in the
lungs where it is needed most. It also reduces the potential for
side effects occurring in other parts of the body, as the amount
absorbed into the blood through the lungs is lower than if it
is taken by mouth.
Salbutamol when used as an inhaler is known as
a reliever. This is because it works very quickly to relieve asthma
attacks or shortness of breath. Salbutamol inhalers can also be
used to open the airways shortly before exercising.
Salbutamol tablets are sometimes prescribed if
inhaled salbutamol is being used frequently to relieve shortness
of breath. The tablets are taken regularly to help keep the airways
open all the time and reduce the need for the inhaler.
How should Ventolin (Albuterol)
be used ?
Ventolin comes as tablets, extended-release (long-acting)
tablets, and syrup to take by mouth and as an aerosol, solution,
and powder-filled capsules to inhale by mouth. The solution is
inhaled using a nebulizer, and the powder-filled capsules are
inhaled using a special dry powder inhaler. Ventolin tablets and
syrup are usually taken three or four times a day, and extended-release
tablets are usually taken twice a day. The oral inhalation is
usually used every 4 to 6 hours for the treatment or prevention
of asthma symptoms. It is used 15 minutes before exercise when
used for the prevention of bronchospasm during exercise. Follow
the directions on your prescription label carefully, and ask your
doctor or pharmacist to explain any part you do not understand.
Take Ventolin exactly as directed. Do not take more or less of
it or take it more often than prescribed by your doctor.
Do not chew or crush the extended-release tablets; swallow them
Ventolin controls symptoms of asthma and other
lung diseases but does not cure them. Do not stop taking Ventolin
without talking to your doctor.
Before you use the Ventolin inhaler for the first
time, read the written instructions that come with it. Ask your
doctor, pharmacist, or respiratory therapist to show you how to
use it. Practice using the inhaler while he or she watches.
- If this medicine fails to provide up to 3 hours
relief from shortness of breath, seek medical advice.
- Inhalers may cause an unexpected increase in wheezing (paradoxical
bronchospasm) straight after using them. If this happens, stop
using the inhaler immediately and consult your doctor. The medicine
should be stopped and an alternative treatment found.
- Blood potassium levels should be monitored in people with severe
asthma, as low oxygen levels in the blood (hypoxia) and various
asthma medicines, including this one, can lower blood potassium.
Use with caution in
- Heart disease
- High blood pressure (hypertension)
- Irregular heart beats (arrhythmias)
Not to be used in
Known sensitivity or allergy to any ingredient
This medicine should not be used if you are allergic to one or
any of its ingredients. Please inform your doctor or pharmacist
if you have previously experienced such an allergy.
If you feel you have experienced an allergic
reaction, stop using this medicine and inform your doctor or pharmacist
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy
or breastfeeding. However, other medicines may be safely used
in pregnancy or breastfeeding providing the benefits to the mother
outweigh the risks to the unborn baby.Always inform your doctor
if you are pregnant or planning a pregnancy, before using any
- This medicine should be used with caution during
pregnancy, and only if the expected benefit to the mother is greater
than any possible risk to the foetus. Seek medical advice from
- This medicine passes into breast milk in small amounts. The
effect of this on the breastfed baby is unknown, therefore this
medicine should be used with caution in breastfeeding mothers.
Discuss with your doctor.
Medicines and their possible side effects can
affect individual people in different ways. The following are
some of the side effects that are known to be associated with
this medicine. Because a side effect is stated here, it does not
mean that all people using this medicine will experience that
or any side effect.
- Faster than normal heart beat (tachycardia)
- Unexpected narrowing of the airways (paradoxical bronchospasm)
- Low blood potassium level (hypokalaemia)
- Shaking, usually of the hands (tremor)
- Anxiety and restlessness
- Awareness of your heart beat (heart palpitations)
The side effects listed above may not include
all of the side effects reported by the drug's manufacturer.
For more information about any other possible
risks associated with this medicine, please read the information
provided with the medicine or consult your doctor or pharmacist.
How can this medicine affect other
This medicine should not be taken with beta-blockers,
such as atenolol, propranolol or timolol. This is because beta-blockers
have an opposite action to this medicine and cause the airways
to narrow. This can result in breathing difficulties for people
with asthma or chronic obstructive airways disease.
Salbutamol can potentially cause a serious decrease
in the levels of potassium in the blood (hypokalaemia), which
may result in adverse effects. This effect can be increased by
the following medicines:-
- xanthine derivates, such as theophylline
- corticosteroids, such as beclometasone and prednisolone
- diuretics, such as bendrofluazide and frusemide
- other beta 2 agonists, such as salmeterol.
Tab Adult 1-2 tab. Childn 1/2-1 tab tid-qid.
Syr Adult 2 tsp, up to 4 tsp. Childn >12 yr 1-2 tsp, 6-12 yr
1 tsp, 2-6 yr 1/2-1 tsp. All doses to be taken tid-qid. Nebules
2.5-5 mg up to qid. Adult Up to 40 mg/day under strict medical
supervision. Evohaler 1-2 puff qid. Resp soln Adult 0.5-1 mL diluted
to a vol of 2-2.5 mL or 2 mL to be used undiluted qid. Continuous
administration: 50-100 mcg/mL administered at a rate of 1-2 mg/hr.
Childn <12 yr 0.5 mL diluted to a vol of 2-2.5 mL. Max: 1 mL
to be repeated qid. Inj Severe bronchospasm & status asthmaticus
Adult 500 mcg SC/IM 4 hrly as required or 250 mcg by slow IV bolus
or infusion. Repeat as required. Status asthmaticus 3-20 mcg/min
by IV infusion.
The preferred antidote for overdosage with salbutamol
is a cardioselective b-blocking agent. However, b-blocking drugs
should be used with caution in patients with a history of bronchospasm.
Hypokalaemia may occur following overdosage with salbutamol. Serum
potassium levels should be monitored.
Respirator Solution: During continuous administration of Ventolin
respirator solution, any signs of overdosage can be usually counteracted
by withdrawal of the drug.
When you miss a dose
Take the forgotten dose as soon as you remember;
then take any remaining doses for that day at equally spaced intervals.
Never take a double dose.
Tablet: Store at a temperature not exceeding
30 C. Store in a dry place and replace cap securely.
Syrup: Store at a temperature not exceeding
30 C. Protect from light.
Expectorant Syrup: Store at a temperature not exceeding 25 C.
Protect form light. Ventolin expectorant may be diluted with unpreserved
syrup BP. The resulting mixture should be protected from light
and will keep for 14 days.
Respirator Solution: Store at a temperature
below 25 C. Protect form light. Once the bottle has been opened,
the contents should be discarded after 1 month.
Evohaler: Store below 30 C. Protect from frost
and direct sunlight.
Nebules: Store at a temperature below 30 C.
Protect from light. Any unused solution in the chamber of the
nebuliser must be discarded.
Injection: Store below 30 C. Protect from light.
All unused admixtures of Ventolin parenteral preparations with
infusion fluids should be discarded 24 hrs after preparation.
Ventolin (Albuterol)(Advance Information)
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